SIRNA DUPLEX



siRNAs are 21-23 nt duplexes that guide RISC to cleave target mRNA. Tsingke provides conventional and modified siRNA from µg to kg scale.





HIGHLIGHTS OF sirna duplex

MS molecular weight detection with an error margin of less than 0.1% HPLC purity detection ensures purity levels greater than 90%;



A high modification rate is achieved, and stable groups such as Ps, 2-F, 2-OMe, and FAM are incorporated into the siRNA oligonucleotides to ensure suitability for downstream applications.



Leverage Tsingke's comprehensive industry chain advantages to provide fast and cost-effective services;



Multi-channel synthesizer with μg to kg level synthesis capabilities, synthesizing over 100,000 siRNA oligos annually.



SERService Details Length(nt) Quantity Purification QC Deliverable

siRNA Custom siRNA synthesis 20~25 5 nmol or 2 OD HPLC HPLC Tube or customized lyophilized RNA

COA report (electronic)

siRNA NC Various types available: negative/positive control siRNA, transfection control siRNA, etc 2.5 nmol/ 1OD

3 siRNA, 1 Guaranteed With a transfection efficiency of 90%, at least one out of the three siRNAs should achieve an mRNA interference efficiency of over 70% 5 nmol or 2 OD

4 siRNA, 1 Guaranteed With a transfection efficiency of 90%, at least one out of the four siRNAs should achieve an mRNA interference efficiency of over 70% 5 nmol or 2 OD

Large-scale siRNA Up to kg level ≥20 nmol or 8 O VICE DETAILS OF SIRNA DUPLEX



*Note: In addition to the recommended content, custom RNA oligo synthesis allows for the customization of length and purification methods.









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